Document Number: 20070300330
Abstract:
A process for replicating or for replicating and expressing a sequence of interest in a plant, comprising: (i) an RNA replicon or a precursor thereof, said RNA replicon being derived from a plus-sense single stranded RNA virus and comprising at least one sequence of interest; and (ii) a helper replicon, or a precursor thereof, wherein said helper replicon is (a) incapable of systemic movement in said plant both in the presence and in the absence of said RNA replicon (i) and (b) capable of expressing in a plant one or more proteins necessary for systemic movement of said RNA replicon (i), whereby said RNA replicon (i) is capable of replicating or replicating and expressing said sequence of interest in said plant, but unable to move systemically in said plant in the absence of said one or more proteins expressed by said helper replicon (ii).
Application Number: 10586998
Primary Class: 800294000
Sub-Classes: 536023600, 536023720, 800298000, 800317000, 800317300
Inventors: Sylvestre Marillonnet, Halle, DE; Carola Engler, Halle, DE; Victor Klimyuk, Halle, DE; Yuri Gleba, Halle, DE
Assignee: Icon Genetics AG, Munchen, DE
Attorney, Agent or Firm: ALSTON & BIRD LLP, BANK OF AMERICA PLAZA, CHARLOTTE, NC, 28280-4000, US
Priority: EP: 04001460.7, 2004-01-23
PCT: WO PCT/EP05/00492, 2005-01-19
Filing Date: 2005-01-19
Publication Date: 2007-12-27
PDF: 20070300330
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