Document Number: 20080155716
Abstract:
The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.
Application Number: 11949874
Primary Class: 800300
Sub-Classes: 536 232, 4353201, 530370
Inventors: Uwe SONNEWALD, Quedlinburg, DE; Frederik BORNKE, Quedlinburg, DE; Kirsten DEIST, Westdorf, DE; Marc Stitt NIGEL, Potsdam, DE; Wolfgang LEIN, Potsdam, DE; Thomas EHRHARDT, Speyer, DE; Andreas REINDL, Mannheim, DE; Ralf-Michael SCHMIDT, Kirrweiler, DE; Annette FREUND, Limburgerhof, DE
Assignee: BASF Aktiengesellschaft, Ludwigshafen, DE
Attorney, Agent or Firm: ROTHWELL, FIGG, ERNST & MANBECK, P.C., 1425 K STREET, N.W., SUITE 800, WASHINGTON, DC, 20005, US
Priority: DE: 10212469.8, 2002-03-20
Filing Date: 2007-12-04
Publication Date: 2008-06-26
PDF: 20080155716
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