Supplemented and unsupplemented tissue sealants, methods of their production and use

Document Number: RE039321

Abstract:

This invention provides a fibrin sealant dressing, wherein said fibrin sealant may be supplemented with at least one composition selected from, for example, one or more regulatory compounds, antibody, antimicrobial compositions, analgesics, anticoagulants, antiproliferatives, antiinflammatory compounds, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like. Also disclosed are methods of preparing and/or using the unsupplemented or supplemented fibrin sealant dressing.

Application Number: 10465853

Primary Class: 424 944

Sub-Classes: 424 941, 424 9464, 530380, 530381, 530382, 530383, 530399, 514 2, 514 54

Inventors: Martin J. MacPhee, North Potomac, MD, US; William N. Drohan, Springfield, VA, US; Gene Liau, Darnestown, MD, US; Hernan Nunez, Derwood, MD, US; Wilson H. Burgess, Clifton, VA, US; Jeffrey O. Hollinger, Gibsonia, PA, US; Thomas Maciag, Freeport, ME, US

Assignee: The American National Red Cross, Rockville, US

Examiners: Jean C. Witz (primary)

Filing Date: 2003-06-20

Publication Date: 2006-10-03

PDF: RE039321

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